For a full list of publications, patents, thesis, and conference abstracts, see Google Scholar.
Y.L. Zhou*, Y. Sang*, L. Xu*, C. Ren*, W. Meng, Y. Zhang, H. Liang, Z. Bao# (2025) Efficient clustered, regularly interspaced short palindromic repeats-based gene activation using combinatorial human transcription activation domains.Protein & Cell In Press.
Y. Sang*, L. Xu*, Z. Bao# (2024) Development of artificial transcription factors and their applications in cell reprograming, genetic screen, and disease treatment.Molecular Therapy 32 (12), 4208-4234.
Z. Cai*, W. Xie*, Z. Bao# (2024) Broadening the targetable space: engineering and discovery of PAM-flexible Cas proteins.Trends in Microbiology 32 (8), 728-731.
L. Deng, Y. Zhou, Z. Cai, J. Zhu, Z. Li, Z. Bao# (2024) Massively parallel CRISPR-assisted homologous recombination enables saturation editing of full-length endogenous genes in yeast.Science Advances 10 (20), eadj9382.
Z. Bao, M. HamediRad, P. Xue, H. Xiao, I. Tasan, R. Chao, J. Liang, H. Zhao# (2018) Genome-scale engineering of Saccharomyces cerevisiae with single nucleotide precision.Nature Biotechnology 36 (6), 505-508.
Highlighted by U.S. Department of Energy, AAAS, Illinois News Bureau, etc.
Z. Bao, S. Jain, V. Jaroenpuntaruk, H. Zhao# (2017) Orthogonal genetic regulation in human cells using chemically induced CRISPR/Cas9 activators.ACS Synthetic Biology 6 (4), 686-693.
Z. Bao*, H. Xiao*, J. Liang, L. Zhang, X. Xiong, N. Sun, T. Si, H. Zhao# (2015) Homology-Integrated CRISPR-Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae. ACS Synthetic Biology 4 (5), 585-594.
Z. Bao*, R. E. Cobb*, H. Zhao# (2016) Accelerated genome engineering through multiplexing.Wiley Interdisciplinary Reviews Systems Biology and Medicine 8 (1), 5-21.
H. Xiao*, Z. Bao*, H. Zhao# (2015) High throughput screening and selection methods for directed enzyme evolution.Industrial & Engineering Chemistry Research 54 (16), 4011-4020.